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ALCOHOL

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ALCOHOL

BJPsych Articles:

Davidson, K.M. (1995) Diagnosis of depression in alcohol dependence: changes in prevalence with drinking status. British Journal of Psychiatry, 166, 199-204

Conclusions It is suggested that depression is largely associated with the episode of drinking which led to admission in patients who are dependent on alcohol and may be due to the effect of chronic alcohol intoxication. Socio-demographic and alcohol related characteristics appear to bear little relation to the presence of depression. Clinicians exercise appropriate judgement in not prescribing antidepressant treatments to patients whose depression may remit with abstinence from alcohol.

 

Michael, A., Mirza, S., Mirza K.A.H., et al (1995) Morbid Jealousy in Alcoholism. British Journal of Psychiatry, 167, 668-672.

Conclusions Alcoholism appears to have an aetiological role in the development of morbid jealousy. Detecting morbid jealousy when it is expressed only under the influence of alcohol has preventative implications.

 

Post, F. (1996) Verbal Creativity, Depression and Alcoholism An Investigation of One Hundred American and British Writers. British Journal of Psychiatry, 168, 545-555.

Conclusions A hypothesis is developed, which links the greater frequency of affective illnesses and alcoholism in playwrights and prose writers, in comparison with poets, to differences in the nature and intensity of their emotional imagination. This hypothesis could be tested by clinical psychologists collaborating with experts in literature on random samples of different kinds of writers.

 

Cook, C.C.H., Palsson, G., Turner, A., et al (1996) A Genetic Linkage Study of the D2 Dopamine Receptor Locus in Heavy Drinking and Alcoholism. British Journal of Psychiatry, 169, 243-248.

Conclusions The results do not support the linkage between the DRD2 locus and alcoholism in most of the families studied. It remains possible that this locus influences the predisposition to alcoholism in some families.

 

Roy, A. (1996) Aetiology of secondary depression in male alcoholics. British Journal of Psychiatry, 169, 753-757.

Conclusion  Having recent life events, particularly events with negative impact, and a family history of depression are risk factors for secondary depression in alcoholics.

 

Pelc, I., Verbanck, P., Le Bon, O., et al. (1997) Efficacy and safety of acamprosate in the treatment of detoxified alcohol-dependent patients A 90-day placebo-controlled dose-finding study. British Journal of Psychiatry, 171, 73-77.

Conclusion This study confirms that acamprosate could be an interesting adjuvant for maintaining abstinence in detoxified alcoholics.

 

Howard, L., Fahy, T. (1997) Liver transplantation for alcoholic liver disease – Editorial. British Journal of Psychiatry, 171, 497-500.

 

Liu, S., Cheng, T.A., (1998) Alcohol use disorders among the Yami aborigines in Taiwan An inter-ethnic comparison. British Journal of Psychiatry, 172, 168-174

Conclusions The lower prevalences of AUDs in Yami than in other aboriginal groups in Taiwan might be explained by social isolation of the former, and differences in drinking tradition, availability of alcohol, biological vulnerability, and the extent of acculturation between these groups.

 

Lingford-Hughes, A.R, Acton, P.D., Gacinovic, S., et al (1998) Reduced levels of GABA-benzodiazepine receptor in alcohol dependency in the absence of grey matter atrophy. British Journal of Psychiatry, 173, 116-122.

Conclusions Alcohol dependency is associated with reduced GABA-benzodiazepine receptor levels in the absence of grey matter atrophy in some cortical regions, such as within the parietal lobe. Regional variability of reduction in GABA-benzodiazepine receptors demonstrates that alcohol does not have a global, toxic effect on the brain.

 

Nutt, D. (1999) Alcohol and the brain Pharmacological insights for psychiatrists. British Journal of Psychiatry, 175, 114-119.

Conclusions An understanding of pharmacology of alcohol use may lead to greater ability to treat psychiatric consequences of alcoholism, and may also prevent some of the secondary psychiatric comorbidity and later brain damage.

 

Haynes, J.C., Farrell, M., Singleton, N., et al (2005) Alcohol consumption as a risk factor for anxiety and depression Results from the longitudinal follow-up of the National Psychiatric Morbidity Survey. British Journal of Psychiatry, 187, 544-551.

Conclusions Excessive alcohol consumption was not associated with the onset of anxiety and depression but abstinence was associated with a lower risk. Sub-threshold symptoms were weakly associated with new-onset alcohol dependence.

 

BMJ Articles:

Babor, T.F. (2008) Tackling alcohol misuse in the UK Higher alcohol taxes and restricting availability are essential. British Medical Journal, 336, 455,

 

Parker, A.J.R., Marshall, E.J., Ball, D.M. (2008) Diagnosis and management of alcohol use disorders. British Medical Journal, 336, 496-501.

 

Groves, T. (2008) Half bottle or half cut? Views and Reviews. British Medical Journal, 336, 507.

 

http://etoh.niaaa.nih.gov/

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) has created this portal to support researchers and practitioners searching for information related to alcohol research. This page includes links to a number of databases, journals, and Web sites focused on alcohol research and related topics. Also included is a link to the archived ETOH database, the premier Alcohol and Alcohol Problems Science Database, produced by NIAAA from 1972 through December 2003.

RCPsych Literature Search ALCOHOL 2005

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RCPsych Literature Search ALCOHOL 2006

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RCPsych Literature Search ALCOHOL 2007

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RCPsych Literature Search ALCOHOL 2009

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RCPsych Literature Search ALCOHOL 2010

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THE NATURAL HISTORY AND PATHOPHYSIOLOGY OF WERNICKE’S ENCEPHALOPATHY AND KORSAKOFF’S PSYCHOSIS

 

 

 

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