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NICOTINE

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NICOTINE:

BJPsych Articles:

Scottish Schizophrenia Research Group (2000) Smoking habits and plasma lipid peroxide and vitamin E levels in never-treated first episode patients with schizophrenia. British Journal of Psychiatry, 176, 290-293.

Conclusions As a result of the high prevalence of smoking this group shows increased lipid peroxidation. Low serum ratios of vitamin E to cholesterol in both patients and controls suggest an unsatisfactory diet.

 

Corvin, A., O’Mahony, E., O’Regan, M., et al (2001) Cigarette smoking and psychotic symptoms in bipolar affective disorder. British Journal of Psychiatry, 179, 35-38.

Conclusion A link between smoking and psychosis exists and may be independent of categorical diagnosis.

 

Carmen Aguilar, M., Gurpegui, M., Diaz, F.J., et al (2005) Nicotine dependence and symptoms in schizophrenia Naturalistic study of complex interactions. British Journal of Psychiatry, 186, 215-221.

Conclusions The data do not generally support the self-medication hypothesis  but rather suggest a complex interaction between nicotine dependence and schizophrenic symptoms.

 

Button, T.M.M., Thapar, A., McGuffin, P. (2005) Relationship between antisocial behaviour, attention-deficit hyperactivity disorder and maternal prenatal smoking. British Journal of Psychiatry, 187, 155-160.

 

Tsoi, D.T., Porwal, M., Webster, C.A. (2010) Efficacy and safety of bupropion for smoking cessation and reduction in schizophrenia: systematic review and meta-analysis. British Journal of Psychiatry, 196, 346-353.

Conclusions Bupropion increases the rates of smoking abstinence in smokers with schizophrenia, without jeopardising their mental state.

 

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