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CANNABIS

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CANNABIS:

Hall, W., Solowij, N. (1997) Long-term cannabis and mental health - Editorial. British Journal of Psychiatry, 171, 107-108.

 

Rey, J.M., Sawyer, M.G., Raphael, P., et al (2002) Mental Health of teenagers who use cannabis. British Journal of Psychiatry, 180, 216-221.

Conclusion Cannabis use is very prevalent. The association with depression, conduct problems and use if other drugs sows a malignant pattern of comorbidity that may lead to negative outcomes.

 

Arsenault, L., Cannon, M., Witton., J et al (2004) Causal association between cannabis and psychosis: examination of the evidence. British Journal of Psychiatry, 184, 110-117.

Conclusions Cases of psychotic disorder could be prevented by discouraging cannabis use among vulnerable youths. Research is needed to understand the mechanism by which cannabis causes psychosis.

 

Daily Cannabis Smoking as a Risk Factor for Progression of Fibrosis in Chronic Hepatitis C, Hepatology, 2005

 

Green, B., Young, R., Kavanagh, D. (2005) Cannabis use and misuse prevalence among people with psychosis. British Journal of Psychiatry, 187, 306-313.

Conclusions The factor most consistently associated with increased odds of cannabis prevalence was specificity of diagnosis. Factors such as consumption patters and study design merit further consideration.

 

Hides, L., Dawe, S., Kavanagh, D.J., et al (2006) Psychotic symptom and cannabis relapse in recent onset psychosis. British Journal of Psychiatry, 189, 137-143.

Conclusions The relationship between cannabis use and psychosis may be bidirectional, highlighting the need for early intervention programmes to target cannabis use and psychotic symptom severity in this population.

 

Yucel, M., Solowij, N., Respondek, C., et al (2008) Regional Brain Abnormalities Associated With Long-term Heavy Cannabis Use. Archives Gen Psychiatry, 65(6), 694-701

http://archpsyc.ama-assn.org/cgi/content/abstract/65/6/694

Conclusions These results provide new evidence of exposure-related structural abnormalities in the hippocampus and amygdala in long-term heavy cannabis users and corroborate similar findings in the animal literature. These findings indicate that heavy daily cannabis use across protracted periods exerts harmful effects on brain tissue and mental health.

 

Forum: decriminalization versus criminalization of cannabis, Current Opinion in Psychiatry, 2008

 

The effect of cannabis on the brain: can it cause brain anomalies

that lead to increased risk for schizophrenia? Current Opinion in Psychiatry, 2008

 

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